Granulocyte Specific Marker (clone BM-2), anti-human, macaque monkey

Source:
A BALB/c nuclei from Pokeweed mitogen stimulated human peripheral blood lymphocytes were used as immunogen.
Fusion partner: NS-1.

Specifications:
Until recently, immunological markers for myeloid cells have been lacking, especially those which identify different levels of cellular differentiation. The BM series provides a new panel of monoclonal antibodies which stain early precursor and mature forms of human myeloid cells. This panel of monoclonal antibodies reacts with antigenic determinants present in normal myeloid cells and leukemias of similar derivation. BM-2 recognizes a cytoplasmic antigen expressed in mature human granulocytes (polys) residing in lymphoid and non-lymphoid tissues. It does not react with any other cell type in human tissues.

Species reactivity:
Positive: human, macaque monkey.

Applications:
For use on formalin-fixed, paraffin embedded tissue. Blood or bone marrow is the recommended positive control tissue.
Flow cytometry: +
Frozen sections: +
Paraffin sections: Citrate

Positive control: Tonsil.

References:
- Epstein, AL et al. Blood 70:1124-1130 (1987).