Granzyme B (clone B18.1), anti-human antibody

Granzyme B (clone B18.1), anti-human antibody

€325.00
In stock
SKU
AC-ABV10053-100
Catalog Number: AC-ABV10053-100
Size: 100 µg
Host: Mouse IgG
Applications: WB, IHC, FC, IP
Datasheet

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Background:
Granzyme B is a 27 kDa serine protease stored in granules of activated cytotoxic T cells and NK cells. Upon target cell contact, granzyme B is directionally exocytosed and assisted by perforin, enters the target cell. With its unique substrate specificity (granzyme B cleaves after Asp), granzyme B processes and activates various pro-caspases thereby inducing apoptosis in the target cell.

Other Names:
Granzyme B, 3.4.21.79, C11, CTLA-1, Cathepsin G-like 1, CTSGL1, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, HLP, SECT, T-cell serine protease 1-3E, GZMB, CGL1, CSPB, CTLA1, GRB

Primary Accession: P10144

Gene Name: GZMB

Gene ID: 3002

Concentration (mg/ml): 0.5 mg/ml
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