Granzyme B polyclonal, anti-human, mouse, rat antibody
€275.00
In stock
SKU
AC-ABV10054-100
Catalog Number: AC-ABV10054-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
Request Information
Background:
Granzyme B is a 27 kDa serine protease stored in granules of activated cytotoxic T cells and NK cells. Upon target cell contact, granzyme B is directionally exocytosed and assisted by perforin, enters the target cell. With its unique substrate specificity (granzyme B cleaves after Asp), granzyme B processes and activates various pro-caspases thereby inducing apoptosis in the target cell.
Other Names:
Primary Accession: P10144
Other Accession: NP_004122
Gene Name: GZMB
Gene ID: 3002
Concentration (mg/ml): 0.5 mg/ml
Granzyme B is a 27 kDa serine protease stored in granules of activated cytotoxic T cells and NK cells. Upon target cell contact, granzyme B is directionally exocytosed and assisted by perforin, enters the target cell. With its unique substrate specificity (granzyme B cleaves after Asp), granzyme B processes and activates various pro-caspases thereby inducing apoptosis in the target cell.
Other Names:
Primary Accession: P10144
Other Accession: NP_004122
Gene Name: GZMB
Gene ID: 3002
Concentration (mg/ml): 0.5 mg/ml
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