Granzyme M polyclonal antibody, anti-human, mouse, rat

Background:
Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene.

Research Area: Cell biology

Synonyms: Granzyme M , EC 3.4.21.-, Met-1 serine protease, Hu-Met-1, Met-ase, Natural killer cell granular protease, Granzyme M, EC 3.4.21.-, Met-1 serine protease, Hu-Met-1, Met-ase, Natural killer cell granular protease

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year