GRAP polyclonal, anti-human

Background:
This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain.

Other Names:
GRB2-related adapter protein, GRAP

Antigen Types:
Synthetic Peptide

Gene Name:
GRAP (HGNC:4562)
Gene ID:
10750
Primary Accession: Q13588
Other Accession: NP_006604;10750;71520 (mouse);