Grap Polyclonal Antibody
€0.00
In stock
SKU
ELK-ES4549
Catalog Number: ELK-ES4549
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-p, ELISA
Information
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Reactivity: Human, Mouse, Rat
Applications: WB, IHC-p, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Background:
GRB2-related adaptor protein(GRAP) Homo sapiens This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway. [provided by RefSeq, Jul 2012],
Alternative Names:
GRAP, GRB2-related adapter protein
Immunogen: The antiserum was produced against synthesized peptide derived from human GRAP. AA range:1-50
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 28
GeneID: GRAP
Storage: -20°C/1 year
NOTE: For Research Use Only
GRB2-related adaptor protein(GRAP) Homo sapiens This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway. [provided by RefSeq, Jul 2012],
Alternative Names:
GRAP, GRB2-related adapter protein
Immunogen: The antiserum was produced against synthesized peptide derived from human GRAP. AA range:1-50
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 28
GeneID: GRAP
Storage: -20°C/1 year
NOTE: For Research Use Only
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