GRB10 (phospho Tyr67) Polyclonal Antibody

Background:
growth factor receptor bound protein 10(GRB10) Homo sapiens The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010],

Alternative Names:
GRB10, GRBIR, KIAA0207, Growth factor receptor-bound protein 10, GRB10 adapter protein, Insulin receptor-binding protein Grb-IR

Immunogen: The antiserum was produced against synthesized peptide derived from human GRB10 around the phosphorylation site of Tyr67. AA range:33-82

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 67

GeneID: GRB10

Storage: -20°C/1 year

NOTE: For Research Use Only