GRB10 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
GRB10, Growth factor receptor-bound protein 10, also known as insulin receptor-binding protein Grb-IR is a protein that in humans is encoded by the GRB10 gene. The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors(e.g., IGF1R and IGF2R). Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified.

Description:
Rabbit IgG polyclonal antibody for Growth factor receptor-bound protein 10 (GRB10) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
grb 10 antibody, GRB IR antibody, grb-10 antibody, GRB10 adapter protein antibody, GRB10 adaptor protein antibody, GRB10 antibody, GRB10_HUMAN antibody, GRBIR antibody, Growth factor receptor bound protein 10 antibody, Growth factor receptor-bound protein 10 antibody, Insulin receptor binding protein antibody, Insulin receptor binding protein GRB IR antibody, Insulin receptor-binding protein Grb-IR antibody, IRBP antibody, KIAA0207 antibody, Maternally expressed gene 1 antibody, MEG1 antibody, RSS antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human GRB10, identical to the related rat and mouse sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Reactivity: human, mouse, rat. No cross reactivity with other proteins.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.