GRB14 polyclonal (N-Term), anti-human
€0.00
In stock
SKU
AC-AP22374a
Catalog Number: AC-AP22374a
Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB57897
Applications: WB, FC, IF
Datasheet
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Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB57897
Applications: WB, FC, IF
Datasheet
Request Information
Background:
Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.
Other Names:
Growth factor receptor-bound protein 14, GRB14 adapter protein, GRB14
Target/Specificity:
This GRB14 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 14-48 amino acids from the human region of human GRB14.
Antigen Type: Synthesized Peptide
Gene Name: GRB14
Gene ID: 2888
Primary Accession: Q14449
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.
Other Names:
Growth factor receptor-bound protein 14, GRB14 adapter protein, GRB14
Target/Specificity:
This GRB14 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 14-48 amino acids from the human region of human GRB14.
Antigen Type: Synthesized Peptide
Gene Name: GRB14
Gene ID: 2888
Primary Accession: Q14449
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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