GRIA2 N-terminal region polyclonal, anti-human, mouse, rat, rabbit, horse, bovine, guinea pig

Background:
Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Other Names:
Glutamate receptor 2, GluR-2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2, GRIA2, GLUR2

Immunogen:
The immunogen for anti-GRIA2 antibody: synthetic peptide directed towards the N terminal of human GRIA2

Gene Name:
GRIA2 (HGNC:4572)
Gene Name:
2891
NCBI Accession:
NP_000817
Primary Accession: P42262
Other Accession: NM_000826;NP_000817
Purification: Protein A purified
Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.