GRIA4 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Glutamate receptor 4 also named GRIA4 or GLUR4, is a protein that in humans is encoded by the GRIA4 gene. It is mapped to 11q22.3. This gene is a member of a family of L-glutamate-gated ion channels that mediate fast synaptic excitatory neurotransmission. These channels are also responsive to the glutamate agonist, alpha-amino-3-hydroxy-5-methyl-4-isoxazolpropionate (AMPA). Some haplotypes of this gene show a positive association with schizophrenia. What's more, glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels.

Description:
Rabbit IgG polyclonal antibody for Glutamate receptor 4 (GRIA4) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
AMPA 4 antibody, AMPA selective glutamate receptor 4 antibody, AMPA-selective glutamate receptor 4 antibody, AMPA4 antibody, GluA 4 antibody, GluA4 antibody, GluR 4 antibody, GluR D antibody, GluR-4 antibody, GluR-D antibody, GluR4 antibody, GLUR4C antibody, GLURD antibody, Glutamate receptor 4 antibody, Glutamate receptor ionotrophic AMPA 4 antibody, Glutamate receptor ionotropic antibody, GRIA 4 antibody, Gria4 antibody, GRIA4_HUMAN antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human GRIA4 recombinant protein (Position: Q176-K350). Human GRIA4 shares 99% amino acid (aa) sequence identity with both mouse and rat GRIA4.E.coli-derived human GRIA4 recombinant protein (Position: Q176-K350). Human GRIA4 shares 99% amino acid (aa) sequence identity with both mouse and rat GRIA4.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse, rat.
Predicted to work with: human.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.