GRIK1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Glutamate receptor, ionotropic, kainate 1, also known as GLUR5, is a protein that in humans is encoded by the GRIK1 gene. It is mapped to 21q21.3. This gene encodes one of the many ionotropic glutamate receptor (GluR) subunits that function as a ligand-gated ion channel. The specific GluR subunit encoded by this gene is of the kainate receptor subtype. Receptor assembly and intracellular trafficking of ionotropic glutamate receptors are regulated by RNA editing and alternative splicing. These receptors mediate excitatory neurotransmission and are critical for normal synaptic function. Exons of this gene are interspersed with exons from the C21or f41 gene, which is transcribed in the same orientation as this gene but does not seem to encode a protein.

Description:
Rabbit IgG polyclonal antibody for Glutamate receptor ionotropic, kainate 1 (GRIK1) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
EAA3 antibody, EEA3 antibody, Excitatory amino acid receptor 3 antibody, GLR5 antibody, GluR-5 antibody, GluR5 antibody, GluR6 antibody, GluR7 antibody, Glutamate receptor 5 antibody, Glutamate receptor antibody, Glutamate receptor ionotropic kainate 1 antibody, GRIK1 antibody, GRIK1_HUMAN antibody, Human glutamate receptor GLUR5 antibody, ionotropic kainate 1 antibody, OTTHUMP00000096569 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human GRIK1 recombinant protein (Position: R271-I450). Human GRIK1 shares 88% and 94% amino acid (aa) sequences identity with mouse and rat GRIK1, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.