GRIK2 (GluR6) polyclonal antibody, anti-human

Background:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation.

Research Area: Neuroscience, Signal transduction

Synonyms: Glutamate receptor, ionotropic kainate 2 , Excitatory amino acid receptor 4, EAA4, Glutamate receptor 6, GluR-6, GluR6, Glutamate receptor, ionotropic kainate 2, Excitatory amino acid receptor 4, EAA4, Glutamate receptor 6, GluR-6, GluR6

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year