GRIK2 polyclonal, anti-human, mouse, rat

Background:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive cognitive disability.

Synonyms: EAA4, GLR6, MRT6, GLUK6, GLUR6, GluK2

Cellular Location: Membrane

Immunogen:
A synthetic peptide of human GRIK2

Gene Symbol: GRIK2

Gene ID: 2898

Swiss prot: Q13002

Calculated MW: 102/98/66/94/77kDa

Recommended dilution:
IHC 1:30-150

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.