GRIK2 Polyclonal Antibody

Background:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation.

Research Area: Cancer, Neuroscience

Synonyms:
GRIK2, EAA4, GLR6, GLUK6, GLUR6, GluK2, MRT6, kainate 2

Immunogen: Recombinant fusion protein of human GRIK2 (NP_068775.1).

Swissprot: Q13002
Gene ID: 2898

Calculated MW: 66 kDa/77 kDa/93 kDa/97 kDa/100 kDa/102 kDa
Observed MW: 115 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.