GRIK2 polyclonal (C-term), anti-human

Background:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation.

Other Names:
Glutamate receptor ionotropic, kainate 2, GluK2, Excitatory amino acid receptor 4, EAA4, Glutamate receptor 6, GluR-6, GluR6, GRIK2, GLUR6

Target/Specificity:
This GRIK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 828-856 amino acids from the C-terminal region of human GRIK2.

Antigen Region:
828-856

Antigen Type: Synthetic Peptide

Gene Name: GRIK2
Gene ID: 2898
Primary Accession: Q13002
NCBI Accession: NP_001159719.1;NP_068775.1;NP_786944.1
Other Accession: Q91755; P42260; P39087; Q38PU3; NP_786944.1; NP_068775.1; NP_001159719.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.