GRIK3 Polyclonal Antibody

Background:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.

Research Area: Neuroscience

Synonyms:
EAA5, Excitatory amino acid receptor 5, GLR 7, GLR7, GLU R7, GLUR 7, GluR 7a, GluR-7, GluR7, GluR7a, Glutamate receptor 7, Glutamate receptor, Glutamate receptor ionotropic kainate 3, GRIK 3, GRIK3, GRIK3, ionotropic kainate 3

Immunogen: Synthetic peptide of human GRIK3

Swissprot: Q13003
Gene Accession: NP000822

Calculated MW: 104 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.5 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.