GRIN2A Polyclonal Antibody

Background:
This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Neuroscience

Synonyms:
EPND, FESD, GluN2A, Glutamate [NMDA] receptor subunit epsilon-1, Glutamate receptor, Glutamate receptor ionotropic N methyl D aspartate 2A, GRIN 2A, GRIN2A, hNR2A, LKS, N methyl D aspartate receptor channel, subunit epsilon 1, N Methyl D Aspartate Receptor Subtype 2A, N methyl D aspartate receptor subunit 2A, N-methyl D-aspartate receptor subtype 2A, NMDA receptor subtype 2A, NMDAR 2A, NMDAR2A, NMDE1, NR2A, OTTHUMP00000160135, OTTHUMP00000174531

Immunogen: Synthetic peptide of human GRIN2A

Swissprot: Q12879
Gene Accession: NP_000824

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: IHC 1:25-100, ELISA 1:2000-5000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-1468/sc-31540/sc-31541/sc-31542/sc-31539/sc-9056