GRIN2B Polyclonal Antibody

Background:
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.

Research Area: Cancer, Neuroscience

Synonyms:
AW490526, EIEE27, Glutamate [NMDA] receptor subunit epsilon 2, Glutamate [NMDA] receptor subunit epsilon-2, Glutamate Receptor Ionotropic N Methyl D Aspartate 2B, Glutamate Receptor Ionotropic N Methyl D Aspartate subunit 2B, Glutamate receptor ionotropic NMDA2B, Glutamate receptor subunit epsilon 2, Glutamate receptor, ionotropic, NMDA2B (epsilon 2), GRIN 2B, GRIN2B, hNR 3, hNR3, MGC142178, MGC142180, MRD6, N methyl D asparate receptor channel subunit epsilon 2, N methyl D aspartate receptor subtype 2B, N methyl D aspartate receptor subunit 2B, N methyl D aspartate receptor subunit 3, N-methyl D-aspartate receptor subtype 2B, N-methyl-D-aspartate receptor subunit 3, NMDA NR2B, NMDA R2B, NMDAR2B, NMDE2, NMDE2, NME2, NR2B, NR3

Immunogen: Synthetic peptide of human GRIN2B

Swissprot: Q13224
Gene Accession: NP_000825

Calculated MW: 166 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-31543/sc-31545/sc-1469/sc-9057