GRK2 (clone 3F8-G6-C11), anti-human

Background:
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008]

Synonyms: ADRBK1, BARK1, BETA-ARK1

Cellular Location: Cell membrane Cytoplasm

Immunogen:
Purified recombinant human GRK2 protein fragments expressed in E.coli.

Gene Symbol: GRK2

Gene ID: 156

Swiss prot: P25098

Calculated MW: 80kDa

Recommended dilution:
WB 1:500

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.