GRM2 polyclonal (C-Term), anti-human

Background:
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.

Other Names:
Metabotropic glutamate receptor 2, mGluR2, GRM2, GPRC1B, MGLUR2

Target/Specificity:
This GRM2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 681-715 amino acids from the human region of human GRM2.

Antigen Type: Synthesized Peptide

Gene Name: GRM2 (HGNC:4594)
Gene ID: 2912
Primary Accession: Q14416
Other Accession: P31421
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.