GRM5 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.

Synonyms: GPRC1E, MGLUR5, PPP1R86, mGlu5

Cellular Location: Cell membrane Multi-pass membrane protein

Immunogen:
Recombinant protein of human GRM5

Gene Symbol: GRM5

Gene ID: 2915

Swiss prot: P41594

Calculated MW: 132kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.