GRM5 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.

Synonyms: mGlu5, GPRC1E, MGLUR5, PPP1R86

Cellular Location: Cell membrane

Immunogen:
A synthetic peptide of human GRM5

Gene Symbol: GRM5

Gene ID: 2915

Swiss prot: P41594

Calculated MW: 132 kDa/128 kDa/105 kDa

Recommended dilution:
IHC 1:25-100

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.