GRM5 Polyclonal Antibody

Background:
This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Neuroscience, Signal Transduction

Synonyms:
GRM5, GPRC1E, MGLUR5, PPP1R86, mGlu5

Immunogen: Recombinant fusion protein of human GRM5 (NP_001137303.1).

Swissprot: P41594
Gene ID: 2915

Calculated MW: 105 kDa/128 kDa/132 kDa
Observed MW: 132 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.