GRO alpha polyclonal antibody, anti-human, mouse, rat

Background:
This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.

Research Area: Neuroscience, Signal transduction, Stem cells, Immunology

Synonyms: Growth-regulated alpha protein , C-X-C motif chemokine 1, GRO-alpha, 1-73, Melanoma growth stimulatory activity, MGSA, Neutrophil-activating protein 3, NAP-3 [Cleaved into: GRO-alpha, 4-73, GRO-a, Growth-regulated alpha protein, C-X-C motif chemokine 1, GRO-alpha, 1-73, Melanoma growth stimulatory activity, MGSA, Neutrophil-activating protein 3, NAP-3, GRO-alpha, 4-73, GRO-alpha, 5-73, GRO-alpha, 6-73,

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year