Growth Hormone (clone GH/1450), anti-human

Background:
Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).

Other Names:
GH; GH-N; GH1; GHN; Growth hormone 1; Growth hormone; Growth hormone, pituitary; HG1; hGH-N; IGHD1B; Pituitary growth hormone; RNGHGP; Somatotropin

Antigen Type:
Recombinant protein

Gene Name: GH1
Gene ID: 2688
Primary Accession: P01241
Other Accession: 655229