GRP78 BiP HSPA5 monoclonal, anti-human, mouse, rat
€455.00
In stock
SKU
AC-ABO13957
Catalog Number: AC-ABO13957
Size: 100 µl
Isotype: Rabbit IgG
Applications: WB, IHC, IF, ICC
Datasheet
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Size: 100 µl
Isotype: Rabbit IgG
Applications: WB, IHC, IF, ICC
Datasheet
Request Information
Description: Anti-GRP78 BiP HSPA5 Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Protein Function:
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate..
Other Names: Endoplasmic reticulum chaperone BiP, 3.6.4.10, 78 kDa glucose-regulated protein, GRP-78, Binding-immunoglobulin protein {ECO:0000303|Ref.4}, BiP {ECO:0000303|Ref.4}, Heat shock protein 70 family protein 5, HSP70 family protein 5, Heat shock protein family A member 5 {ECO:0000312|HGNC:HGNC:5238}, Immunoglobulin heavy chain-binding protein {ECO:0000303|Ref.4}, HSPA5 (HGNC:5238)
Clone Name(s):
Clone: BOO-8
Subcellular Localization: Endoplasmic reticulum lumen. Melanosome. Cytoplasm. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Gene ID: 3309
Immunogen: A synthesized peptide derived from human GRP78 BiP
Calculated MW: 72333
Purification: Affinity-chromatography
Format: Liquid
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Protein Function:
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate..
Other Names: Endoplasmic reticulum chaperone BiP, 3.6.4.10, 78 kDa glucose-regulated protein, GRP-78, Binding-immunoglobulin protein {ECO:0000303|Ref.4}, BiP {ECO:0000303|Ref.4}, Heat shock protein 70 family protein 5, HSP70 family protein 5, Heat shock protein family A member 5 {ECO:0000312|HGNC:HGNC:5238}, Immunoglobulin heavy chain-binding protein {ECO:0000303|Ref.4}, HSPA5 (HGNC:5238)
Clone Name(s):
Clone: BOO-8
Subcellular Localization: Endoplasmic reticulum lumen. Melanosome. Cytoplasm. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Gene ID: 3309
Immunogen: A synthesized peptide derived from human GRP78 BiP
Calculated MW: 72333
Purification: Affinity-chromatography
Format: Liquid
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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