GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) (clone SPM249 ), anti-human, mouse, rat, rabbit, Ha, primate, pig, chicken, bovine, sheep, X, horse, guinea pig, D

Background:
Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grp s are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.

Other Names:
Endoplasmin, 94 kDa glucose-regulated protein, GRP-94, Heat shock protein 90 kDa beta member 1, Tumor rejection antigen 1, gp96 homolog, HSP90B1, GRP94, TRA1

Gene Name: HSP90B1 (HGNC:12028)
Gene ID: 7184
Primary Accession: P14625
Other Accession: 7184, 192374