GRPEL2 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71169
Background:
GrpEL2 (GrpE protein homolog 2) is a 225 amino acid mitochondrial matrix protein and component of the PAM complex. Consisting of Tim44, Tim14, HSP 70, Magmas, GrpEL1 and GrpEL2, the PAM complex plays an essential role in the ATP-dependent translocation of transit peptide-containing proteins to the mitochondrial matrix from the inner membrane. GrpEL2 regulates the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins and stimulates its ATPase activity. The gene encoding GrpEL2 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome.
Alternative Name:
GrpE protein homolog 2, mitochondrial, Mt-GrpE#2, GRPEL2
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: GRPEL2 polyclonal antibody detects endogenous levels of GRPEL2 protein.
Immunogen:
Recombinant protein of human GRPEL2.
MW: ~ 25 kDa
Swis Prot.: Q8TAA5
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
GrpEL2 (GrpE protein homolog 2) is a 225 amino acid mitochondrial matrix protein and component of the PAM complex. Consisting of Tim44, Tim14, HSP 70, Magmas, GrpEL1 and GrpEL2, the PAM complex plays an essential role in the ATP-dependent translocation of transit peptide-containing proteins to the mitochondrial matrix from the inner membrane. GrpEL2 regulates the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins and stimulates its ATPase activity. The gene encoding GrpEL2 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome.
Alternative Name:
GrpE protein homolog 2, mitochondrial, Mt-GrpE#2, GRPEL2
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: GRPEL2 polyclonal antibody detects endogenous levels of GRPEL2 protein.
Immunogen:
Recombinant protein of human GRPEL2.
MW: ~ 25 kDa
Swis Prot.: Q8TAA5
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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