GSDMB Polyclonal Antibody

Background:
This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Alternative splicing and the use of alternative promoters results in multiple transcript variants. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding.

Research Area: Cell Biology

Synonyms:
GSDMB, GSDML, PP4052, PRO2521

Immunogen: Recombinant fusion protein of human GSDMB (NP_001159431.1).

Swissprot: Q8TAX9
Gene ID: 55876

Calculated MW: 18 kDa/45 kDa/46 kDa/47 kDa
Observed MW: 47 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.