GSR polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS8047
Background:
Glutathione reductase, also designated Glutathione reductase mitochondrial precursor, GRase, GSR or GR, belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. The main function of the protein is to maintain high levels of reduced glutathione in the cytosol. With the concomitant oxidation of NADPH, Glutathione reductase transforms oxidized glutathione to the reduced form. Glutathione reductase, which can localize to mitochondria or to the cytoplasm, can form a disulfide-linked homodimer. The active site of the protein is a redox-active disulfide bond.
Alternative Name:
Glutathione reductase, mitochondrial, GR, Grase, GSR, GLUR, GRD1
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: GSR polyclonal antibody detects endogenous levels of GSR protein.
Immunogen:
Recombinant full length Human GSR.
MW: ~ 56 kDa
Swis Prot.: P00390
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Glutathione reductase, also designated Glutathione reductase mitochondrial precursor, GRase, GSR or GR, belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. The main function of the protein is to maintain high levels of reduced glutathione in the cytosol. With the concomitant oxidation of NADPH, Glutathione reductase transforms oxidized glutathione to the reduced form. Glutathione reductase, which can localize to mitochondria or to the cytoplasm, can form a disulfide-linked homodimer. The active site of the protein is a redox-active disulfide bond.
Alternative Name:
Glutathione reductase, mitochondrial, GR, Grase, GSR, GLUR, GRD1
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: GSR polyclonal antibody detects endogenous levels of GSR protein.
Immunogen:
Recombinant full length Human GSR.
MW: ~ 56 kDa
Swis Prot.: P00390
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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