GSR Polyclonal Antibody

Background:
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

Research Area: Cancer, Cell Biology, Metabolism, Signal Transduction

Synonyms:
GLR1, GLUR, Glutathione reductase, Glutathione reductase mitochondrial, Glutathione reductase, mitochondrial, GR, Gr1, GRase, GRD 1, GRD1, GSHR, GSR, MGC78522

Immunogen: Recombinant protein of human GSR

Swissprot: P00390
Gene Accession: BC069244

Calculated MW: 56 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:1000-1:5000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-32406/sc-32408/sc-32886