GST3 polyclonal, anti-human, mouse, rat

Background:
Glutathione S-transferases (GSTs) function in the metabolic detoxification of various environmental carcinogens and lipid hydroperoxides. In response to oxidative stress, upregulation of the GST family member GSTP1 occurs, consistent with this function. Furthermore, the GSTP1 gene is subject to CpG island hypermethylation, a state that correlates with human prostatic carcinogenesis. GSTP1 gene hypermethylation can be detected in urine, ejaculate and plasma from men with prostate cancer, potentially making GSTP1 a useful biomarker for prostate cancer screening.

Alternative Name:
GSTP1, FAEES3, GST3, Deafness, Deafness X-linked 7, DFN7, FAEES3, Fatty Acid Ethyl Ester Synthase III, Glutathione S Transferase 3, Glutathione S Transferase Pi, Glutathione S-transferase P, Glutathione S-transferase pi 1, GST class-pi, GST3, GSTP, Gstp1, GSTP1-1, GSTP1, PI, X linked 7,

Application Dilution:
WB:1:500-1:1,000
ICC:1:500-1:1,000
IHC:1:50-1:200

Specificity: GST3 polyclonal antibody detects endogenous levels of GST3 protein.

Immunogen:
Recombinant protein with human GST3 aa 1-150.

MW: 23 kDa

Swiss-Prot: P09211(Human) P19157(Mouse) P04906(Rat)

Purification & Purity:
Protein affinity purified.

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.