GSTA1 Polyclonal Antibody

Background:
This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. This action is an important step in detoxification of these compounds. This subfamily of enzymes has a particular role in protecting cells from reactive oxygen species and the products of peroxidation. Polymorphisms in this gene influence the ability of individuals to metabolize different drugs. This gene is located in a cluster of similar genes and pseudogenes on chromosome 6. Alternative splicing results in multiple transcript variants.

Research Area: Signal Transduction, Tags & Cell Markers, Metabolism

Synonyms:
Glutathione S alkyltransferase A1, Glutathione S transferase 2, Glutathione S transferase Ha subunit 1, GST class-alpha member 1, GST epsilon, GST HA subunit 1, GST-epsilon, GST2, GSTA1-1, GSTA1, GTH1, HA subunit 1, MGC131939

Immunogen: Recombinant Rat Glutathione S-transferase alpha-1 protein

Swissprot: P00502
Gene ID: 24422

Calculated MW: 25 kDa
Observed MW: 25 kDa

Purification Method: Antigen Affinity Purification

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: WB 1:3000-1:6000 IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.