GSTA3 Polyclonal Antibody

Background:
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity.

Research Area: Metabolism, Signal Transduction

Synonyms:
Glutathione S alkyltransferase A3, Glutathione S aralkyltransferase A3, Glutathione S aryltransferase A3, Glutathione S transferase A3 3, Glutathione S transferase A3, glutathione S transferase A3 subunit, Glutathione S transferase alpha 3, Glutathione S transferase alpha type (Ya), glutathione S transferase Yc 1, glutathione S transferase Yc1 subunit, Glutathione S-transferase A3, Glutathione S-transferase A3-3, Glutathione S-transferase Ya3, Glutathione S-transferase Yc, glutathione transferase A3 subunit, Glutathione transferase alpha 3, GST 2 2, GST AA, GST class alpha, GST class alpha member 3, GST class-alpha member 3, GST Yc1, GSTA 3, GSTA3 3, Gsta3, GSTA3-3, GSTA3, Gstyc, GTA 3, GTA3, MGC22232, S (hydroxyalkyl)glutathione lyase A3, Yc1

Immunogen: Recombinant protein of human GSTA3

Swissprot: Q16772
Gene Accession: BC020619

Calculated MW: 25 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.