GTF2F2 polyclonal, anti-human, mouse

GTF2F2 polyclonal, anti-human, mouse

€388.00
In stock
SKU
BS7884
Catalog Number: BS7884
Size: 50 ul, 100 ul
Isotype: rabbit IgG
Applications: WB, IHC, IF

Datasheet
Background:
In eukaryotic systems, initiation of transcription from protein-coding genes is a complex process requiring RNA polymerase II and broad families of auxiliary transcription factors. Such factors can be divided into two major functional classes: the basal factors that are required for transcription of all Pol II genes, including TFIIA, TFIIB, TFIID, TFIIE, TFIIF and TFIIH; and sequence-specific factors that regulate gene expression. The basal transcription factors and Pol II form a specific multiprotein complex near the transcription start site by interacting with core promotor elements such as the TATA box generally located 25-30 base pairs upstream of the transcription start site. TFIIF, a heteromer composed of a small (RAP 30) and a large (RAP 74) subunit, is required for RNA polymerase II to assemble into a preinitiation complex formed by promotor DNA and the general factors TFIID, IIA and IIB. In addition, TFIIF stimulates transcription elongation by RNA polymerase II.

Alternative Name:
ATP dependent helicase GTF2F2, ATP-dependent helicase GTF2F2, BTF4, General transcription factor IIF 30 kDa subunit, General transcription factor IIF polypeptide 2, General transcription factor IIF subunit 2, General transcription factor IIF, polypeptide 2, 30kDa, Gtf2f2, RAP30, T2FB_HUMAN, TF2F2, TFIIF, TFIIF beta, TFIIF-beta, Transcription initiation factor IIF subunit beta, Transcription initiation factor RAP30,

Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200

Specificity: GTF2F2 polyclonal antibody detects endogenous levels of GTF2F2 protein.

Immunogen:
Recombinant full length Human GTF2F2.

MW: ~ 30 kDa

Swis Prot.: P13984

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.
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