GTF2I Polyclonal Antibody

Background:
This gene encodes a phosphoprotein containing six characteristic repeat motifs. The encoded protein binds to the initiator element (Inr) and E-box element in promoters and functions as a regulator of transcription. This locus, along with several other neighboring genes, is deleted in Williams-Beuren syndrome. There are many closely related genes and pseudogenes for this gene on chromosome 7. This gene also has pseudogenes on chromosomes 9, 13, and 21. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
BAP 135, BAP-135, BAP135, Bruton tyrosine kinase associated protein 135, Bruton tyrosine kinase-associated protein 135, BTK associated protein 135, BTK associated protein 135kD, BTK associated protein, BTK-associated protein 135, BTKAP 1, BTKAP1, DIWS, FLJ38776, FLJ56355, General transcription factor II i, General transcription factor II-I, General transcription factor IIi, GTF 2I, Gtf2i, GTF2I, GTFII I, GTFII-I, IB 291, IB291, SPIN, SRF Phox 1 interacting protein, SRF Phox1 interacting protein, SRF-Phox1-interacting protein, TFII-I, Transcription factor II I, WBS, WBSCR 6, WBSCR6, Williams Beuren syndrome chromosome region 6, Williams Beuren syndrome chromosome region 6 protein, Williams-Beuren syndrome chromosomal region 6 protein

Immunogen: Synthetic peptide of human GTF2I

Swissprot: P78347
Gene Accession: NP_127492

Calculated MW: 112 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-9943/sc-9944/sc-28716