GTF3A antibody (clone 4G4), anti-human

Background:
The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein.

Other Names:
Transcription factor IIIA, TFIIIA, GTF3A

Antigen Type:
Recombinant Protein

Gene Name: GTF3A
Gene ID: 2971
NCBI Accession: NP_002088.2
Primary Accession: Q92664
Other Accession: NM_002097
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .