GTP-CH-1 Peptide
€133.00
In stock
SKU
350575
Protein Family: Enzymes
Pathway and Disease: Cofactor and Vitamin Metabolism
Alternate Names: GCH-1; GTP cyclohydrolase I; GTP-CH-1; GTP cyclohydrolase 1
Accession No.: P30793
Description:
GCH-1 catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. The final product (BH4) is an essential co-factor for three aromatic amino acid monooXygenases (F,Y, and W). Isoform GCH-1 is the functional enzyme.
Format:
Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
MW: 1625.8 g/mol
Sequence:
The synthetic peptide used to raise the antibody Cat. No. 250680 is selected from a sequence within the N-term region of human GTP-CH-1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Composition:
C72H116N22O21
Purity:
> 80% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Pathway and Disease: Cofactor and Vitamin Metabolism
Alternate Names: GCH-1; GTP cyclohydrolase I; GTP-CH-1; GTP cyclohydrolase 1
Accession No.: P30793
Description:
GCH-1 catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. The final product (BH4) is an essential co-factor for three aromatic amino acid monooXygenases (F,Y, and W). Isoform GCH-1 is the functional enzyme.
Format:
Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
MW: 1625.8 g/mol
Sequence:
The synthetic peptide used to raise the antibody Cat. No. 250680 is selected from a sequence within the N-term region of human GTP-CH-1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Composition:
C72H116N22O21
Purity:
> 80% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
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