GUCY1B2 Antibody(N-term) Blocking peptide

GUCY1B2 Antibody(N-term) Blocking peptide

€363.00
In stock
SKU
AC-BP7135a
Catalog Number: AC-BP7135a
Size: 500 µg
Datasheet
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Background:
Nitric oxide-sensitive guanylyl cyclase is a heterodimeric enzyme consisting of an alpha and a beta subunit. The enzyme converts GTP into the second messenger cGMP and plays a major role in the cardiovascular system as a receptor for nitric oxide. Unlike other guanylyl cyclases, GUCY1B2 contains an 86-amino acid C-terminal extension with a consensus sequence for isoprenylation/carboxymethylation.

Other Names:
Guanylate cyclase soluble subunit beta-2, GCS-beta-2, GUCY1B2

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7135a was selected from the N-term region of human GUCY1B2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: GUCY1B2
Primary Accession: O75343
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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