GUCY2D antibody (clone 1000000), anti-human
€435.00
In stock
SKU
AC-AT2301a
Catalog Number: AC-AT2301a
Size: 100 µg
Isotype: mouse IgG
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG
Applications: WB, IF, E
Request Information AC-AT2301a">Request Information
Background:
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.
Other Names:
Retinal guanylyl cyclase 1, RETGC-1, Guanylate cyclase 2D, retinal, Rod outer segment membrane guanylate cyclase, ROS-GC, GUCY2D, CORD6, GUC1A4, GUC2D, RETGC, RETGC1
Antigen Type:
Recombinant Protein
Gene Name: GUCY2D
Gene ID: 3000
NCBI Accession: NP_000171.1
Primary Accession: Q02846
Other Accession: NM_000180
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.
Other Names:
Retinal guanylyl cyclase 1, RETGC-1, Guanylate cyclase 2D, retinal, Rod outer segment membrane guanylate cyclase, ROS-GC, GUCY2D, CORD6, GUC1A4, GUC2D, RETGC, RETGC1
Antigen Type:
Recombinant Protein
Gene Name: GUCY2D
Gene ID: 3000
NCBI Accession: NP_000171.1
Primary Accession: Q02846
Other Accession: NM_000180
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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