GUCY2D polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS70554
Background:
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.
Alternative Name:
LCA, CYGD, LCA1, RCD2, CORD5, CORD6, GUC2D, ROSGC, retGC, GUC1A4, RETGC-1, ROS-GC1,
Application Dilution: WB: 1:200 - 1:2000
Specificity: GUCY2D polyclonal antibody detects endogenous levels of GUCY2D protein.
Immunogen:
Recombinant protein of human GUCY2D.
MW: ~ 120 kDa
Swis Prot.: Q02846
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.
Alternative Name:
LCA, CYGD, LCA1, RCD2, CORD5, CORD6, GUC2D, ROSGC, retGC, GUC1A4, RETGC-1, ROS-GC1,
Application Dilution: WB: 1:200 - 1:2000
Specificity: GUCY2D polyclonal antibody detects endogenous levels of GUCY2D protein.
Immunogen:
Recombinant protein of human GUCY2D.
MW: ~ 120 kDa
Swis Prot.: Q02846
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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