GUCY2D polyclonal (Center), anti-human, rat

GUCY2D polyclonal (Center), anti-human, rat

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In stock
SKU
AC-AP11569c
Catalog Number: AC-AP11569c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19346
Applications: WB, IHC-P, FC
Datasheet

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Background:
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq].

Other Names:
Retinal guanylyl cyclase 1, RETGC-1, Guanylate cyclase 2D, retinal, Rod outer segment membrane guanylate cyclase, ROS-GC, GUCY2D, CORD6, GUC1A4, GUC2D, RETGC, RETGC1

Target/Specificity:
This GUCY2D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 540-570 amino acids from the Central region of human GUCY2D.

Antigen Region:
540-570

Antigen Type: Synthetic Peptide

Gene Name: GUCY2D
Gene ID: 3000
Primary Accession: Q02846
NCBI Accession: NP_000171.1
Other Accession: NP_000171.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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