GUF1 Polyclonal Antibody

GUF1 Polyclonal Antibody

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In stock
SKU
ELK-ES7055
Catalog Number: ELK-ES7055
Reactivity: Human
Applications: IHC-p, ELISA
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Background:
GUF1 homolog, GTPase(GUF1) Homo sapiens This gene encodes a GTPase that triggers back-translocation of the elongating ribosome during mitochondrial protein synthesis. The protein contains a highly conserved C-terminal domain not found in other GTPases that facilitates tRNA binding. The encoded protein is thought to prevent misincorporation of amino acids in stressful, suboptimal conditions. An allelic variant in this gene has been associated with early infantile epileptic encephalopathy-40. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016],

Alternative Names:
GUF1, Translation factor GUF1, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1, Ribosomal back-translocase

Immunogen: The antiserum was produced against synthesized peptide derived from human GUF1. AA range:421-470

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

GeneID: GUF1

Storage: -20°C/1 year

NOTE: For Research Use Only
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