GZMA Polyclonal Antibody

Background:
Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells.

Research Area: Cancer, Cell Biology, Immunology

Synonyms:
GZMA, CTLA3, HFSP

Immunogen: Recombinant fusion protein of human GZMA (NP_006135.1).

Swissprot: P12544
Gene ID: 3001

Calculated MW: 27 kDa/28 kDa
Observed MW: 35 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.