GZMM Polyclonal Antibody

Background:
GZMM (Granzyme M) is a Protein Coding gene. Diseases associated with GZMM include Adrenal Insufficiency, Congenital, With 46Xy Sex Reversal, Partial Or Complete and Congenital Adrenal Insufficiency. Among its related pathways are Innate Immune System and Granzyme Pathway. GO annotations related to this gene include serine-type endopeptidase activity and endopeptidase activity. An important paralog of this gene is CFD.Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene.

Research Area: Cell Biology

Synonyms:
GRAM, Granzyme M (lymphocyte met ase 1), Granzyme M, GranzymeM, GZM M, Gzmm, HU Met 1, HU-Met-1, LMET 1, LMET1, Lymphocyte met ase 1, MET 1, Met 1 serine protease, Met ase, Met-1 serine protease, Met-ase, MET1, Met1 serine protease, Natural killer cell granular protease

Immunogen: Synthetic peptide of human GZMM

Swissprot: P51124
Gene Accession: NP005308

Calculated MW: 28 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:20-1:100, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.