H-type 5, 6 (CD 173) (clone HE-182), anti-human

Source:
A B10.A mouse was immunized with human erythrocytes.
Fusion partner: Sp2/0.

Specifications:
HE-182 reacts with human blood group H type 5 and type 6 as confirmed with Chembiomed synthetic oligosaccharide-BSA conjugate in ELISA. It is expressed on endothelial cells, epithelial cells and granulocytes. Increased expression of this antigen has been observed on some tumor tissues such as gastric carcinomas, urothelial carcinomas, and colon carcinomas.

Species reactivity:
Positive: human.

Applications:
Demonstration of blood group H, type 5 and 6. Classification of carcinomas.
ELISA: +
Flow cytometry: +
Frozen sections: +
Immunofluorescence: +
Paraffin sections: +

Positive control: Colon cancer.

References:
- Blood transfusion and immunohaematology, Ph Rouger, D Anstee and Ch Salmon (Eds), Arnette, France 30 (5), p. 353-720, 1987.