H2AFX Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13716b
Background:
Histones are basic nuclear proteins that are responsiblefor the nucleosome structure of the chromosomal fiber ineukaryotes. Two molecules of each of the four core histones (H2A,H2B, H3, and H4) form an octamer, around which approximately 146 bpof DNA is wrapped in repeating units, called nucleosomes. Thelinker histone, H1, interacts with linker DNA between nucleosomesand functions in the compaction of chromatin into higher orderstructures. This gene encodes a member of the histone H2A family,and generates two transcripts through the use of the conservedstem-loop termination motif, and the polyA addition motif.
Other Names:
Histone H2AX, H2a/x, Histone H2AX, H2AFX, H2AX
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13716b was selected from the C-term region of H2AFX. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: H2AX (HGNC:4739)
Gene ID: 3014
Primary Accession: P16104
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Histones are basic nuclear proteins that are responsiblefor the nucleosome structure of the chromosomal fiber ineukaryotes. Two molecules of each of the four core histones (H2A,H2B, H3, and H4) form an octamer, around which approximately 146 bpof DNA is wrapped in repeating units, called nucleosomes. Thelinker histone, H1, interacts with linker DNA between nucleosomesand functions in the compaction of chromatin into higher orderstructures. This gene encodes a member of the histone H2A family,and generates two transcripts through the use of the conservedstem-loop termination motif, and the polyA addition motif.
Other Names:
Histone H2AX, H2a/x, Histone H2AX, H2AFX, H2AX
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13716b was selected from the C-term region of H2AFX. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: H2AX (HGNC:4739)
Gene ID: 3014
Primary Accession: P16104
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
| Is Featured? | No |
|---|
Write Your Own Review