H2AFX polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP13716b
Catalog Number: AC-AP13716b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33675
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33675
Applications: IHC-P, WB
Datasheet
Request Information
Background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
Other Names:
Histone H2AX, H2a/x, Histone H2AX, H2AFX, H2AX
Target/Specificity:
This H2AFX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-140 amino acids from the C-terminal region of human H2AFX.
Antigen Region:
111-140
Antigen Type: Synthetic Peptide
Gene Name: H2AX (HGNC:4739)
Gene ID: 3014
Primary Accession: P16104
NCBI Accession: NP_002096.1
Other Accession: NP_002096.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
Other Names:
Histone H2AX, H2a/x, Histone H2AX, H2AFX, H2AX
Target/Specificity:
This H2AFX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-140 amino acids from the C-terminal region of human H2AFX.
Antigen Region:
111-140
Antigen Type: Synthetic Peptide
Gene Name: H2AX (HGNC:4739)
Gene ID: 3014
Primary Accession: P16104
NCBI Accession: NP_002096.1
Other Accession: NP_002096.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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