H2AFY2 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP20530c
Catalog Number: AC-AP20530c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Applications: WB
Datasheet
Request Information
Background:
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
Other Names:
Core histone macro-H2A2, Histone macroH2A2, mH2A2, H2AFY2, MACROH2A2
Target/Specificity:
This H2AFY2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-169 amino acids from the Central region of human H2AFY2.
Antigen Region:
148-169
Antigen Type: Synthetic Peptide
Gene Name: MACROH2A2 (HGNC:14453)
Gene ID: 55506
Primary Accession: Q9P0M6
NCBI Accession: NP_061119.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
Other Names:
Core histone macro-H2A2, Histone macroH2A2, mH2A2, H2AFY2, MACROH2A2
Target/Specificity:
This H2AFY2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-169 amino acids from the Central region of human H2AFY2.
Antigen Region:
148-169
Antigen Type: Synthetic Peptide
Gene Name: MACROH2A2 (HGNC:14453)
Gene ID: 55506
Primary Accession: Q9P0M6
NCBI Accession: NP_061119.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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